Our current research work is focused on:
- Designing and synthesis of new anti-HIV/AIDS, and anti-hepatitis virus C (HCV) candidates.
- Designing and synthesis of new steriod analogues as inhibitors of cytochrome 450 (CYP) which lead for cancer treatment, especially inhibitors for CYP17 α-hydroxylase for treatment of prostate carcinoma.
- Design and synthesis of novel 1,3,5-triazine analogues for the treatment of pancreatic adenocarcinoma (Capan-1) and colorectal carcinoma (HCT-116), as well as treatment of breast cancer.
- Early tumor diangosis using flourescence imaging methodology, by synthesis of small fluorescent molecules.
- Computational studies including: docking, ADMET, and molecular dynamic studies.
- Conformational analysis of bioactive molecules by molecular modelling study, QSAR and 2D NMR techniques (e.g. COSY, ROSEY, TOSCY, HMQC, HMBC, HSQC)